Connection of standard each and every day sodium and potassium removal that have SBP
Cousin regularity distribution out of (a) SBP alter, (Gaussian match Roentgen 2 getting sodium sensitive = 0.74 and you may salt resistant = 0.97) and you can (b) urinary Na + /K + randki ferzu, (Gaussian fit R 2 to possess sodium sensitive and painful = 0.99 and you may sodium resistant somebody = 0.99) about band of salt sensitive and painful (n = 71) and you will sodium resistant (letter = 119) individuals with change of dieting intervention out-of Weight reduction Methods to Stop Blood pressure (DASH) high sodium (HS) eating plan so you’re able to Dash lower sodium (LS) eating plan.
Certainly one of data users assessed, 53% out-of SR and you will 62% of the SS professionals was indeed female, 51% off SR and you will 63% out-of SS members was in fact African-Western (Table step 1). Many people have been aged 29–55 ages, college-experienced, and you will working regular. There had been no tall variations in baseline qualities for investigation players across ethnicity or intercourse in both brand new SS otherwise SR organizations (Desk step one).
Baseline SBP, assessed during the screening visit prior to dietary intervention was significantly higher in SS (137.6 ± 8.7 mmHg) vs. SR participants (132.5 ± 9.6 mmHg; p < 0.05, Table 2). In contrast there was no significant difference in 24 h urinary Na + excretion, 24 h urinary K + excretion and the urinary Na + :K + ratio between SS and SR participants at screening (Table 2). Further, there was no significant effect of sex or ethnicity on these variables, as such subsequent analyses were not adjusted for age or ethnicity. In SS, but not SR participants, each additional g/day in urinary Na + excretion across the range of <2 g/day to 5 g/day resulted in a higher SBP value of approximately 1.0 ± 0.4 mmHg in SBP/g Na + excretion (Fig. 2a). The measures >5 g/day Na+ were not included due to increased sample variability. When assessed by linear regression across the entire range of observed Na + excretion we observed no correlation between urinary Na + excretion and SBP in either SS (R 2 = 0.02) or SR (R 2 = 0.02) participants (Fig. 2b). (more…)