I identified 59 randomised managed products out-of calcium intake you to said BMD just like the an outcome

I identified 59 randomised managed products out-of calcium intake you to said BMD just like the an outcome

Baseline properties

7 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 Fifteen studied dietary sources of calcium (n=810 calcium, n=723 controls),16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 and 51 studied calcium supplements (n=6547 calcium, n=5710 controls).7 12 13 14 15 17 19 20 21 22 26 28 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 Table 1 ? shows study design and selected baseline characteristics for included studies of dietary calcium. Tables 2 and 3 show the study design and selected baseline characteristics for indiancupid návštěvníků trials of calcium supplements, without and with additional vitamin D, respectively. ? ? Further details are in tables A-C in appendix 2. Of the 15 randomised controlled trials of dietary sources of calcium, 10 used milk or milk powder, two used dairy products, and three used hydroxyapatite preparations. Of the 51 trials of calcium supplements, 36 studied calcium monotherapy, 13 co-administered CaD, and two were multi-arm studies of both. Table 4 summarises other features of the trials ? . Most of them studied calcium without vitamin D in women aged <70 living in the community; the mean baseline dietary calcium intake was <800 mg/day; and most trials lasted ?2 years. A calcium dose of >500 mg/day was used in most trials, but a higher proportion of trials of calcium supplements used a dose of ?1000 mg/day. Table C in appendix 2 shows our assessment of risk of bias. Of the 15 trials of dietary sources of calcium, we assessed two as low risk of bias, six as moderate risk, and seven as high risk. Of the 51 trials of calcium supplements, we assessed 19 as low risk of bias, 12 as moderate risk, and 20 as high risk.

Style of randomised managed examples and you can selected baseline attributes of eligible samples away from calcium that can used vitamin D tablets

First analyses

Table 5 ? summarises the results of your own meta-analyses. Broadening calcium supplements intake of weight loss offer increased BMD because of the 0.6-step one.0% at the full stylish and complete body from the 1 year and you may of the 0.7-step 1.8% from the those web sites and the lumbar back and you may femoral shoulder during the a couple of years (figs step 1 and dos ? ? . There can be no affect BMD in the forearm.

Fig step one Haphazard outcomes meta-research regarding effectation of losing weight resources of calcium towards payment transform for the limbs nutrient density (BMD) of baseline on 1 year

Fig dos Arbitrary effects meta-studies out-of effectation of weight loss sources of calcium supplements towards the payment alter when you look at the limbs nutrient thickness (BMD) away from standard at the 2 yrs

As soon as we restricted new analyses for the several randomised controlled trials of dairy otherwise dairy food, from the excluding around three products regarding hydroxyapatite, there is certainly nothing change in the outcome. Calcium supplements improved BMD at all five skeletal internet sites from the 0.7-step one.4% within 1 year (figs step 3 and you may 4 ? ? ), by the 0.8-step one.5% from the two years (figs 5 and 6 ? ? ), and also by 0.8-step one.8% at the more than two-and-a-half years (fig seven ? ) (directory of time of examples is less than six many years).